Ep. 24: Cellarity Executives on the Fascinating Realm of Cellular-Level Drug Discovery


In this episode, VibeCast host Ray Dogum speaks with Laurens Kruidenier, PhD & Fabrice Chouraqui, PharmD from Cellarity about the fascinating realm of cellular-level drug discovery. The key moments in this episode are: 00:00:00 - Introduction, 00:03:54 - Traditional Drug Discovery, 00:08:06 - Cellular Level Drug Discovery, 00:09:39 - Sickle Cell Disease Example, 00:13:16 - How Cellarity's Platform Works, 00:16:23 - The Revolutionary Potential of the Platform, 00:17:21 - The Inefficiency and Cost of Drug Discovery, 00:18:43 - Efficiency and New Discoveries with the Platform, 00:22:32 - Application of the Platform to Different Diseases, 00:26:55 - Reception from Pharma Companies and Societal Impact, 00:34:09 - Creating a Scientific Community at Cellarity, 00:34:42 - The Changing Landscape of Science, 00:35:40 - Attracting Top Talent to Cellarity, 00:36:53 - Innovation in Biotech Funding, 00:39:53 - The Future of Therapeutic Research. Laurens Kruidenier Bio: Laurens Kruidenier joined Cellarity in December 2021 as CSO. Bringing over 25 years of experience in discovery research, both in academic settings as well as in the life sciences industry, Laurens leads the continued evolution of Cellarity’s platform and pipeline. Laurens also oversees cross functional integration across all aspects of computation, drug discovery and optimization and he contributes to reinforce Cellarity’s external presence in the scientific and investor community. Laurens holds an M.Sc. in Medical Biology from Utrecht University and a Ph.D. in Mucosal Immunology from Leiden University, both in the Netherlands. In his spare time, Laurens enjoys modern & contemporary art, 1970s movies, hiking, sailing, and black & white photography. Fabrice Chouraqui Bio: Fabrice Chouraqui joined Flagship Pioneering in 2020, where he serves as both CEO-Partner of Flagship Pioneering and Chief Executive Officer of Cellarity. He has deep experience across the business spectrum, from R&D to commercial leadership, business development and investor communications. Fabrice was formerly the President of Novartis Pharmaceuticals in the US. Throughout his career at Novartis and Bristol-Myers Squibb, he has led the launch of breakthrough treatments in several areas, including oncology, immunology, neuroscience and cardiovascular. Guest Links: Laurens Kruidenier LinkedIn: https://www.linkedin.com/in/laurens-kruidenier-62b5a99/ Fabrice Chouraqui Linkedin: https://www.linkedin.com/in/fabricechouraqui/ About VibeCast VibeCast is our weekly informational podcast and content series exploring the hottest topics in drug development and Web3 with some of the dynamic people that make up the Vibe community. VibeCast is a collection of long-form and short-form video content intended to help our community learn about the current opportunities and challenges in biotech fundraising and community engagement innovation. Guests will include biotech founders, regulatory experts, drug development executives, blockchain technologists, web3 community builders, patient community advocates, and many other Vibe Bio community members seeking to accelerate the development of breakthrough treatments. Follow Vibe Bio's Socials: https://twitter.com/VibeBio https://www.linkedin.com/company/vibe-bio/ https://www.instagram.com/vibebiotechnology/ https://www.tiktok.com/@vibebio https://www.facebook.com/VibeBiotechnology/ Disclaimer: VibeCast is intended to be used for educational and entertainment purposes, and no information or opinions shared constitute advice or services. While guests are invited to listen, listeners acknowledge they are not being provided professional advice from the podcast or the guests. The podcast is for private non-commercial use and guests do not necessarily reflect any agency, organization, or company that they work for.