Ep. 20: Ethan Perlstein on the Role of Families in Research Funding and 1-to-N Medicine
In this episode, VibeCast host Ray Dogum speaks with Ethan Perlstein, PhD about the Role of Families in Research Funding, 1-to-N Medicine, Clinical Trials, and the Challenges of Funding Rare Disease Research. Guest Bio: Ethan O. Perlstein received a PhD in 2006 from Harvard University (Department of Molecular and Cell Biology) while working in the laboratory of Professor Stuart Schreiber. He completed an independent postdoctoral fellowship at the Lewis-Sigler Institute at Princeton University from 2007 to 2012. Since its founding in 2014, he is CEO of Perlara PBC, the first biotech Public Benefit Corporation partnering with highly motivated families to develop treatments and cures for genetic diseases. Perlara’s first joint venture Maggie’s Pearl is the commercial sponsor of a pivotal Phase 3 trial of epalrestat for the treatment of PMM2-CDG. Guest Links: LinkedIn: https://www.linkedin.com/in/ethan-perlstein-1260545/ Twitter: https://twitter.com/eperlste Perlara Website: https://www.perlara.com/ The key moments in this episode are: 00:00:00 - Intro 00:01:25 - Background 00:03:32 - Working in Academia 00:06:17 - Unique Funding Model for Rare Diseases 00:09:44 - Collaboration with Rare Disease Families 00:15:38 - The Potential of Public Benefit Companies, 00:18:00 - The Benefits of PBCs, 00:18:31 - Personalized Medicine and DTC Biotech, 00:22:51 - One to N Approach in Personalized Medicine, 00:26:16 - Pricing for Guided Medical Attention, 00:30:00 - The Role of Foundations in Biotech Partnerships, 00:31:30 - Web Three Technologies and Patient Ownership, 00:32:31 - Financial Compensation for Clinical Trial Participants, 00:33:52 - The Potential of Web3 in Medicine, 00:38:19 - Shifting Focus to Human Trials and Patient Empowerment About VibeCast VibeCast is our weekly informational podcast and content series exploring the hottest topics in drug development and Web3 with some of the dynamic people that make up the Vibe community. VibeCast is a collection of long-form and short-form video content intended to help our community learn about the current opportunities and challenges in biotech fundraising and community engagement innovation. Guests will include biotech founders, regulatory experts, drug development executives, blockchain technologists, web3 community builders, patient community advocates, and many other Vibe Bio community members seeking to accelerate the development of breakthrough treatments.
Follow Vibe Bio's Socials:
Facebook Disclaimer: VibeCast is intended to be used for educational and entertainment purposes, and no information or opinions shared constitute advice or services. While guests are invited to listen, listeners acknowledge they are not being provided professional advice from the podcast or the guests. The podcast is for private non-commercial use and guests do not necessarily reflect any agency, organization, or company that they work for.
