Ep. 18: Are Biomarkers the Future? Mo Jain, MD, PhD on Small Molecule Biomarkers
In this episode, VibeCast host Ray Dogum speaks with Mo Jain, MD, PhD, Founder and CEO of Sapient, about small molecule biomarkers & innovations in metabolomics. Dr. Jain is a physician-scientist with more than 20 years of expertise in physiology, biomedicine, engineering, computational biology, and mass spectrometry-based metabolomics. Prior to founding Sapient, he formed and was director of Jain Laboratory at the University of California San Diego (UCSD). There he led a multi-disciplinary research team to develop next-generation rapid liquid chromatography-mass spectrometry (rLC-MS) systems to probe the non-genetic landscape of disease across population-scale human studies, supported by over $30M in federal, foundation, and industry funding. Dr. Jain founded Sapient in 2021 as a spinout of Jain Laboratory to expand upon the mission of accelerating human discovery and drug development through the nexus of high throughput analytical mass spectrometry, computational biology, and population-level biomarker profiling. Dr. Jain has held faculty positions at UCSD since 2013, most recently as a Professor of Medicine and Pharmacology. He obtained his MD and PhD from Boston University School of Medicine, and performed clinical residency and fellowship training in Internal Medicine, Cardiology, and Preventative Cardiology at Brigham and Women’s Hospital, Harvard Medical School. Guest Links Linkedin: https://www.linkedin.com/in/mo-jain-md-phd-373895ba/ Sapient Twitter: https://twitter.com/SapientBio Sapient Linkedin: https://www.linkedin.com/company/sapientbio/ The key moments in this episode are: 00:00:00 - Introduction, 00:01:02 - Dr. Mo Jain's Background, 00:03:28 - Importance of Mass Spectrometry, 00:08:11 - Starting Sapient Bio, 00:10:16 - Biomarker Discovery and Therapeutic Research, 00:13:06 - Advancements in Diagnostics Technology, 00:15:05 - Constraints in the Medical Field, 00:16:44 - Future of Medicine, 00:18:12 - Collaboration with the Bill and Melinda Gates Foundation, 00:24:44 - Biotech Funding Landscape, 00:27:02 - The Importance of Profitability and Funding, 00:28:52 - Supply Chain and Manufacturing, 00:29:37 - Partnerships and Clients, 00:31:30 - Reflections on Diagnostics and Funding, 00:31:58 - Final Thoughts and Advice, Follow Vibe Bio's Socials:
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About VibeCast VibeCast is our weekly informational podcast and content series exploring the hottest topics in drug development and Web3 with some of the dynamic people that make up the Vibe community. VibeCast is a collection of long-form and short-form video content intended to help our community learn about the current opportunities and challenges in biotech fundraising and community engagement innovation. Guests will include biotech founders, regulatory experts, drug development executives, blockchain technologists, web3 community builders, patient community advocates, and many other Vibe Bio community members seeking to accelerate the development of breakthrough treatments. Disclaimer: VibeCast is intended to be used for educational and entertainment purposes, and no information or opinions shared constitute advice or services. While guests are invited to listen, listeners acknowledge they are not being provided professional advice from the podcast or the guests. The podcast is for private non-commercial use and guests do not necessarily reflect any agency, organization, or company that they work for.
